PURPOSE:Vogt´s antioxidant solution (red blood cells, Ringer's solution, sodium bicarbonate, mannitol, allopurinol and 50% glucose) or its modification including hydroxyethyl starch (HES) were tested for the prevention of splanchnic artery occlusion shock.METHODS:Seventy rats were distributed in treatment (3), control (1), and sham (3) groups. Ischemia and reperfusion were induced by celiac, superior mesenteric and inferior mesenteric arteries occlusion for 40 min, followed by 60 min reperfusion or sham procedures. Controls received saline, both treatment and sham groups received the Vogt's solution, modified Vogt's solution (replacing Ringer's solution by HES), or HES. Mean arterial blood pressure (MABP), ileal malondialdehyde (MDA) and plasmatic MDA were determined, and a histologic grading system was used.RESULTS:At reperfusion, MABP dropped in all I/R groups. Only HES treatment was able to restore final MABP to the levels of sham groups. Plasmatic MDA did not show differences between groups. Ileum MDA was significantly higher in the control and treatment groups as compared to the sham group. Histology ranking was higher in the only in control group.CONCLUSIONS:Hydroxyethyl starch was able to prevent hemodynamic shock but not intestinal lesions. Both treatments with Vogt's solutions did not show any improvement.

OBJETIVO: Realizou-se um inquérito para comparar diferenças de gênero nos padrões de consumo de álcool em duas amostras urbanas, estratificadas e representativas de duas comunidades (B e RJr). MÉTODO: O questionário Genacis (Gênero, Álcool e Cultura: Um Estudo Internacional Gender, Alcohol, and Culture: An Internacional Study) foi utilizado. RESULTADOS: Houve várias diferenças significativas em dados sociodemográficos e de padrões de uso de álcool entre essas duas amostras. Uma delas tinha população mais velha, educada, católica, branca e mais mulheres na força de trabalho. Dados da comunidade B mostraram que mulheres e homens tiveram padrões similares de consumo de álcool. RJr teve uso de álcool mais alto entre homens e 22% dos homens abaixo de 49 anos de idade tinham padrão de uso do tipo binge. DISCUSSÃO: O acesso, tabagismo, renda e ter um parceiro com consumo pesado de álcool foram fatores de risco importantes para o consumo das mulheres. CONCLUSÕES: Este estudo mostra que quando os papéis das mulheres se tornam similares aos dos homens, modificam seu padrão de consumo de álcool.

OBJECTIVE: A survey was conducted to compare gender differences in patterns of drinking in two stratified, urban and representative samples from two communities (B and RJr). METHOD: The Genacis (Gender, Alcohol, and Culture: an International Study) questionnaire was used. RESULTS: There were several significant differences in the demographics and patterns of alcohol use between these two samples. One had an older, more Catholic, educated, Caucasian population, with more women in the labor force. Data from B community showed that women and men had similar patterns of drinking. RJr had much higher use of alcohol among men, and almost 22% of those under 49 years old were binge drinkers. DISCUSSION: Access, smoking, income and having a heavy drinker partner were important risk factors for women's drinking. CONCLUSIONS: This study shows that when women's roles become more similar to men's, so do their drinking patterns.

Com o objetivo de avaliar a função reprodutiva de 4 cães machos, adultos, a citologia aspirativa com agulha fina (FNAC) e as concentrações de testosterona sérica foram usadas em associação a determinação do volume testicular e análise do sêmen. FNAC foi realizada em ambos os testículos e as concentrações de testosterona foram determinadas durante 24 horas, em intervalos regulares. Os resultados da análise do semen se encontraram dentro do padrão para a espécie nos cães 1 e 3. O cão 2 apresentou testículos pequenos, baixa qualidade seminal, alta porcentagem de células de Sertoli e espermátides iniciais sugerindo uma degeneração testicular. No cão 4 observou-se uma degeneração testicular do lado direito conseqüência de um processo obstrutivo mostrada pela diminuição do testículo, baixa qualidade do sêmen evidenciada pela baixa concentração espermática e incontável número de espermatozóides na FNAC; uma diminuição do trânsito espermático foi observada no testículo esquerdo, com espessamento do epidídimo, alta porcentagem de gotas distais na análise seminal, porém resultados normais na FNAC. O ritmo circadiano da testosteronafoi claro nos cães 3 e 4, entretanto as concentrações encontraram-se próximas ao limite inferior. O volume testicular, a análise do sêmen e a FNAC testicular podem fornecer informações valiosas sobre a espermatogênese. Entretanto, as concentrações séricas de testosterona não são claramente correlacionadas as características reprodutivas nesses cães.

In order to verify alternative clinical approach in the reproductive evaluation of 4 adult dogs, the fine needle aspiration cytology (FNAC) and serum testosterone levels were used together with testicular volume measurement and semen analysis. FNAC was performed in both testes and serum testosterone concentrations were assayed in regular intervals during a 24h period. Results of semen analysis and FNAC were normal in dogs 1 and 3. In dog 2, small testes, poor semen quality, a high percentage of Sertoli cells and early spermatids were found suggesting testicular degeneration. In dog 4, a small right testicle, poor semen quality with low sperm concentration and an uncounted amount of spermatozoa in the FNAC indicated testicular degeneration due to an obstructive lesion; whereas high percentage of distal droplets, thicker left epididymis and normal FNAC of the left testis suggested a slow sperm transit. Testosterone circadian rhythm was clear in 3 of 4 dogs, although concentrations were low. Testicular volume, semen analysis and testicular FNAC could provide valuable information about spermatogenesis. In contrast, serum testosterone concentration was not clearly correlated with any reproductive characteristic of those dogs.

Os efeitos de prostaglandina (PGF2a) vs CIDR e eCG (gonadotrofina coriônica eqüina) na dinâmica folicular da primeira onda e sua relação com as concentrações plasmáticas de P4 e E2 foram investigadas em ovelhas cíclicas. Foram utilizadas 14 fêmeas ovinas da raça Bergamascia; o Grupo 1 (G1) foi submetido a duas aplicações de PGF2alfa e o Grupo 2 (G2), tratado com CIDR durante 14 dias, sendo que, no momento de sua retirada, administraram-se 500 UI de eCG. A dinâmica folicular ovariana foi monitorada por meio de ultra-som. Monitoraram-se todos os folículos > 2mm e mapeou-se sua posição diariamente, observando-se o desenvolvimento individual de cada folículo. Desde o dia anterior à aplicação da segunda dose de PGF2alfa (G1) e desde a administração de eCG (G2) até o décimo dia do ciclo estral, foram coletadas amostras de sangue para análise de P4 e E2. Houve diferença significativa nas concentrações plasmáticas de P4 e E2 entre os tratamentos. A sincronização de estro e ovulação, utilizando CIDR + 500 UI de eCG, incrementou a quantidade de folículos recrutados, além de aumentar o diâmetro máximo e a taxa de crescimento dos folículos grandes na primeira onda folicular.

The effect of prostaglandin (PGF2a) vs CIDR and eCG (equine chorionic gonadotrophin) on follicular dynamic of wave 1 and its relation with P4 and E2 plasma concentrations were investigated in cyclic ewes. Fourteen Bergamascia ewes were used, Group 1 (G1) synchronized by two i.m. injections of PGF2alpha and Group 2 (G2) treated for 14 d with CIDR and 500 IU of eCG at dispositive withdrawal on day 14. Ovarian follicular dynamics were ultrasonically monitored. All the ovarian follicles > 2 mm were measured, and their relative locations were recorded on an ovarian map in order to follow the sequential development of each individual follicle. Blood samples for P4 and E2 determination were collected daily from 1 d before the second injection of PGF2alpha (G1) and administration of eCG (G2) until day 10 after ovulation of the cycle. There were significant differences in P4 and E2 plasma concentrations between treatments. The CIDR + eCG (500 IU) treatment enhanced the recruitment of smaller follicles and enhanced the maximum diameter and growth rate of large follicles during wave 1.

Compliance to antiretroviral medication is a problem for AIDS patients. Compliance can be influenced by the characteristics of the therapeutic program, by the health guidance professionals, by the patient, and by society in general. A group of 139 Brazilian AIDS patients from the Infectious-Parasitic Diseases day clinic at the University Hospital of the Federal University of Mato Grosso do Sul were interviewed from September 27, 1999 to January 21, 2000. We identified and evaluated the frequency of noncompliance to antiretroviral medication, as well as the associated motives. Those who ingested 80%, or more, of prescribed dosages during the week previous to the interview were considered compliant. Among the patients interviewed, 70% mentioned loss or misplacement of medicine, and 63% were considered compliant. Average compliance was 75.8%, with no difference between the sexes. The reasons given for non-compliance were: absent-mindedness or forgetfulness (67.7%), lack of medicine (41.9%), side effects (21.5%), complexity of prescribed regimens (12.9%), fatigue (9.7%), and voluntary interruption (7.5%). The non-compliance observed among these patients indicates that health service personnel should promote activities to recuperate these therapeutic programs, employing methodologies appropriate to the characteristics of this population.